所在团队
方强林
研究方向
噬菌体生物学
教育经历
2020.10-2025.1 巴黎萨克雷大学，生化和结构生物学博士
2017.09-2020.06 中国科学院大学，生物工程硕士
2013.09-2017.06 广东海洋大学，海洋生物学学士
工作经历
2020年7月-9月：科研助理，中科院南海海洋研究所
2023年9月-11月：德国拜耳基金博士生交换项目，马克斯·普朗克生物物理化学研究所
代表性文章
1.Wu X, et al. The complete genome of Vibrio sp. 16 unveils two circular chromosomes and a distinctive 46-kb plasmid. Microbiol Resour Announc. 2024;13(4):e0122223. doi:10.1128/mra.01222-23.
2. Wu X, et al. Transcriptomic analysis of sea cucumber (Holothuria leucospilota) coelomocytes revealed the echinoderm cytokine response during immune challenge. BMC Genomics. 2020 Apr 16;21(1):306. doi: 10.1186/s12864-020-6698-6. PMID: 32299355; PMCID: PMC7161275.
3. Wu X, et al. First echinoderm alpha-amylase from a tropical sea cucumber (Holothuria leucospilota): Molecular cloning, tissue distribution, cellular localization and functional production in a heterogenous E.coli system with codon optimization. PLoS One. 2020 Sep 15;15(9): e0239044. doi: 10.1371/journal.pone.0239044. PMID: 32931501; PMCID: PMC7491741.
4. Li H# , Wu X# , et al. Molecular characterization, inducible expression and functional analysis of an IKKβ from the tropical sea cucumber Holothuria leucospilota. Fish Shellfish Immunol. 2020 Sep; 104:622-632. doi: 10.1016/j.fsi.2020.06.024. Epub 2020 Jun 22. PMID: 32585358. #Co-first author.
5. Pan, W., Wang, X., Ren, C., Jiang, X., Gong, S., Xie, Z., Wong, N. K., Li, X., Huang, J., Fan, D., Luo, P., Yang, Y., Ren, X., Yu, S., Qin, Z., Wu, X., Huo, D., Ma, B., Liu, Y., Zhang, X., … Chen, T. (2024). Sea cucumbers and their symbiotic microbiome have evolved to feed on seabed sediments. Nature communications, 15(1), 8825. https://doi.org/10.1038/s41467-024-53205-5
6. Chen T, Ren C, Wong NK, Yan A, Sun C, Fan D, Luo P, Jiang X, Zhang L, Ruan Y, Li J, Wu X, Huo D, Huang J, Li X, Wu F, E Z, Cheng C, Zhang X, Wang Y, Hu C. The Holothuria leucospilota genome elucidates sacrificial organ expulsion and bioadhesive trap enriched with amyloid-patterned proteins. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2213512120. doi: 10.1073/pnas.2213512120. Epub 2023 Apr 10. PMID: 37036994.
