教授，博士生导师

中山大学公共卫生学院（深圳） 

 

个人简介

主要研究方向为结核病病原生物学和系统流行病学。综合运用病原生物学，基因组学，空间流行病学，生物信息学和数理统计模型等多学科手段，从宿主群体和病原菌方面探究对结核病流行的驱动因素，包括病原菌传播、致病机制及其异质性研究，细菌耐药性的产生、播散和演化机制研究，同时评估其对传染病诊疗和防控的作用。

主持国家科技部重点研发项目课题、国家自然科学基金青年项目、广东省自然基金面上项目、深圳医科院前沿探索项目，NIH-CTSA-KL2，NIH-Fogarty等国内外基金项目。以第一作者或通讯作者在Lancet Infectious Diseases等期刊发表SCI论文80余篇，累计他引超过2500次。

 

教育经历

2008/09-2013/05 复旦大学 病原生物学 博士

2004/09-2008/07 四川大学 生物科学 学士

 

工作经历

2021/05-至今 中山大学公共卫生学院（深圳） 教授

2019/02-2021/04 耶鲁大学公共卫生学院 副研究员

2016/01-2019/01 耶鲁大学公共卫生学院 博士后

2013/07-2015/12 复旦大学基础医学院 博士后

 

部分获奖及荣誉

中国防痨协会科学技术奖二等奖

上海市医学科技青年奖

Robert E. Leet and Clara Guthrie Patterson Trust Award

GloCalFellowship Award

 


发表论文

  1. Yanping Liu, Yangyi Zhang, Xiaoyu Lu, Zheyuan Wu, Minjuan Li, Rui Zhang, Yixiao Lu, Renjie Hou, Yating Ji, Qingping Zhang, Qi Jiang, Jing Li, Yuan Jiang, Yunxia Wang, Jianhui Yuan, Howard E Takiff, Xin Chen, Xin Shen, Chongguang Yang*.Mixed infections and heteroresistance of Mycobacterium tuberculosis among multidrug-resistant tuberculosis in China: a genomic epidemiology study. Emerging Microbes & Infections. 2025.
  2. Xiaoyu Lu, Yuan Jiang, Rui Zhang, Yangyi Zhang, Jing Li, Lili Wang, Qi Ye, Renjie Hou, Yixiao Lu, Xi Zhu, Yating Ji, Mingyu Gan, Minjuan Li, Qingyun Liu, Xin Shen, Chongguang Yang*. Epidemiologic and Bacterial Factors Facilitating Long-Term Transmission of Multidrug-Resistant Tuberculosis in Shanghai, China. Clinical Infectious Diseases.2025.
  3. Lin, H., R. Zhang, Z. Wu, M. Li, J. Wu, X. Shen and C. Yang (2023). Assessing the spatial heterogeneity of tuberculosis in a population with internal migration in China: a retrospective population-based study. Front Public Health 11: 1155146.
  4. Yueting Liu, Ruoyao Sun, Hongyin Zhang, Jinrong Huang, Meiru Chen, Yiqiang Zhan, Jianbang Xiang, Jianhui Yuan, Huachun Zou, Leonardo Martinez, Chongguang Yang. Trends and predictions of tuberculosis notification in mainland China during and after the COVID-19 pandemic. Journal of Infection. 10.1016/j.jinf.2023.10.013
  5. X Wu, X Zhou, Y Chen, K Zhai, R Sun, G Luo, YF Lin, Y Li, C Yang*, H Zou*.The Impact of COVID-19 Lockdown on Cases of and Deaths From AIDS, Gonorrhea, Syphilis, Hepatitis B, and Hepatitis C: Interrupted Time Series Analysis. JMIR Public Health and Surveillance 9, e40591
  6. Yang C, Sobkowiak B, Naidu V, Codreanu A, Ciobanu N, Gunasekera KS, Chitwood MH, Alexandru S, Bivol S, Russi M, Havumaki J, Cudahy P, Fosburgh H, Allender CJ, Centner H, Engelthaler DM, Menzies NA, Warren JL, Crudu V, Colijn C*, Cohen T*. Phylogeography and transmission of M. tuberculosis in Moldova: A prospective genomic analysis.PLoS Med. 2022 Feb 22;19(2):e1003933.
  7. Yang C, Lu L, Warren JL, Wu J, Jiang Q, Zuo T, Gan M, Liu M, Liu Q, DeRiemer K, Hong J, Shen X, Colijn C, Guo X*, Gao Q*, Cohen T*. Internal migration and transmission dynamics of tuberculosis in Shanghai, China: an epidemiological, spatial, genomic analysis. Lancet Infect Dis. 2018 Jul;18(7):788-795.
  8. Yang C, Luo T, Shen X, Wu J, Gan M, Xu P, Wu Z, Lin S, Tian J, Liu Q, Yuan Z, Mei J, DeRiemer K*, Gao Q*. Transmission of multidrug-resistant Mycobacterium tuberculosis in Shanghai, China: a retrospective observational study using whole-genome sequencing and epidemiological investigation. Lancet Infect Dis. 2017 Mar;17(3):275-284.
  9. Yang C, Kang J, Lu L, Guo X, Shen X, Cohen T, Menzies NA. The positive externalities of migrant-based TB control strategy in a Chinese urban population with internal migration: a transmission-dynamic modeling study.BMC Med. 2021 Apr 20;19(1):95. 
  10. X Shen, W Sha, C Yang, Q Pan, T Cohen, S Cheng, Q Cai, X Kan, P Zong, Z Zeng, S Tan, R Liang, L Bai, J Xia, S Wu, P Sun, G Wu, C Cai, X Wang, K Ai, J Liu, Z Yuan. Continuity of TB services during the COVID-19 pandemic in China. Int J Tuberc Lung Dis. 2021 Jan 1;25(1):81-83.
  11. L Lu, Q Jiang, J Hong, X Jin, Q Gao, H Bang, K DeRiemer, C Yang. Catastrophic costs of tuberculosis care in a population with internal migrants in China. BMC Health Services Research 2020 (1), 1-9
  12. Yang C, Shen X, Peng Y, Lan R, Zhao Y, Long B, Luo T, Sun G, Li X, Qiao K, Gui X, Wu J, Xu J, Li F, Li D, Liu F, Shen M, Hong J, Mei J, DeRiemer K, Gao Q. Transmission of Mycobacterium tuberculosis in China: a population-based molecular epidemiologic study.Clin Infect Dis. 2015 Jul 15;61(2):219-27. 
  13. Yang C, Luo T, Sun G, Qiao K, Sun G, DeRiemer K, Mei J, Gao Q. Mycobacterium tuberculosis Beijing strains favor transmission but not drug resistance in China.Clin Infect Dis. 2012 Nov;55(9):1179-87. 
  14. Shen X*, Yang C*, Wu J, Lin S, Gao X, Wu Z, Tian J, Gan M, Luo T, Wang L, Yu C, Mei J, Pan Q, DeRiemer K, Yuan Z, Gao Q. Recurrent tuberculosis in an urban area in China: Relapse or exogenous reinfection?Tuberculosis (Edinb). 2017 Mar;103:97-104.
  15. Chen. C., Yang. C., Gao. X., Lu. Z., Tang. F., Cheng. J., Gao. Q., Cardenas. V. Community-based active case finding for tuberculosis in rural western China: a cross-sectional study. Int J Tuberc Lung Dis. 2017. 21: 1134-39
  16. Xu P, Wu J, Yang C, Luo T, Shen X, Zhang Y, Nsofor CA, Zhu G, Gicquel B, Gao Q. Prevalence and transmission of pyrazinamide resistant Mycobacterium tuberculosis in China.Tuberculosis (Edinb). 2016 May;98:56-61. 
  17. Luo T, Comas I, Luo D, Lu B, Wu J, Wei L, Yang C, Liu Q, Gan M, Sun G, Shen X, Liu F, Gagneux S, Mei J, Lan R, Wan K, Gao Q. Southern East Asian origin and coexpansion of Mycobacterium tuberculosis Beijing family with Han Chinese. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):8136-41. 
  18. Luo T*, Yang C*, Peng Y, Lu L, Sun G, Wu J, Jin X, Hong J, Li F, Mei J, DeRiemer K, Gao Q. Whole-genome sequencing to detect recent transmission of Mycobacterium tuberculosis in settings with a high burden of tuberculosis. Tuberculosis (Edinb). 2014 Jul;94(4):434-40. 
  19. Peng Y*, Yang C*, Li X, Luo T, Li F, Gao Q. Multiple samples improve the sensitivity for detection of mixed Mycobacterium infections.Tuberculosis (Edinb). 2013 Sep;93(5):548-50. 
  20. Sun G, Luo T, Yang C, Dong X, Li J, Zhu Y, Zheng H, Tian W, Wang S, Barry CE 3rd, Mei J, Gao Q. Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients.J Infect Dis. 2012 Dec 1;206(11):1724-33.
  21. Luo T, Yang C, Gagneux S, Gicquel B, Mei J, Gao Q. Combination of single nucleotide polymorphism and variable-number tandem repeats for genotyping a homogenous population of Mycobacterium tuberculosis Beijing strains in China.J Clin Microbiol. 2012 Mar;50(3):633-9
  22. Lan R*, Yang. C*, Lan L, Ou J, Qiao K, Liu F, Gao Q. Mycobacterium tuberculosis and non-tuberculous mycobacteria isolates from HIV-infected patients in Guangxi, China. Int J Tuberc Lung Dis 2011. 15(12): 1669-75 (*Co-first author)
  23. Houben, R., H. Esmail, J. C. Emery, L. R. Joslyn, C. F. McQuaid, N. A. Menzies, J. Sanz, S. Shrestha, R. G. White, C. Yang and F. Cobelens. Spotting the old foe-revisiting the case definition for TB. 2019. Lancet Respir Med 7(3): 199-201. (Review)
  24. Yang. C., Gao. Q. Recent transmission of Mycobacterium tuberculosis in China: the implication of molecular epidemiology for tuberculosis control. 2018. Frontiers of Medicine 12 (1), 76-83 (Review)
     

主持项目

科技部重点研发专项课题

深圳市医科院前沿探索项目

广东省自然科学基金面上项目

NIH-CTSA K12

国自然基金青年项目