博士生导师，中山大学百人计划引进人才

工作经历

2020/01-2021/01        美国匹斯堡大学医学院 研究科学家

2014/09-2020/1          美国哈佛大学医学院Brigham and Women’s Hospital, 博士后

2013/08-2014/08        香港中文大学生物医学科学院，博士后

教育经历

2010/09-2013/07        香港中文大学医学院 生物医学科学 博士

2006/09-2010/07        华中科技大学生命科学与技术学院 生化与分子生物学 硕士

2002/09-2006/07        华中科技大学管理学院 工商管理 学士

2002/09-2006/07        华中科技大学生命科学与技术学院 生物技术 学士

主要承担课题及人才项目

中山大学“百人计划”启动项目，项目负责人

国家自然科学基金 青年项目 2021-2023，主持

社会兼职

学术期刊编委：Food and Nutrition Sciences

学术期刊审稿人：是Circulation Research; Cardiovascular Research; Molecular Therapy; British Journal of Pharmacology; Antioxidants and redox signaling；Journal of Cellular Biochemistry等14本杂志的审稿人。

科研基金评审专家：Hong Kong Research Grants Council ,University of Macau Research Grant,

代表论文

  1. Zhang Y, Guillermier C, Raedt DT, Cox AG, Maertens O, Yimlamai D, Lun M, Whitney A, Fernando D. Camargo, Maas RL, Goessling W, Cichowski K, Steinhauser ML. Imaging mass spectrometry demonstrates a pro-growth signature of tumor metabolic heterogeneity. iScience; 2020; 23(8):101355
  2. Zhang Y, Federation AJ, Kim S, Lun M, O’Keefe JP, Xiang D, Brown JD, Steinhauser ML. Targeting NR4A1-dependent adipocyte progenitor quiescence promotes metabolic adaption to obesity. Journal of clinical investigation. 2018; 128(11):4898-4911

  3. Zhang Y, Liu J, Luo JY, Tian XY, Cheang WS, Xu J, Lau CW, Wang L, Wong WT, Wong CM, Lan HY, Yao X, Raizada MK, Huang Y. Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes. Antioxidants & redox signaling. 2015; 23(11):880-92.

  4. Zhang Y, Liu J, Tian XY, Wong WT, Chen Y, Wang L, Luo J, Cheang WS, Lau CW, Kwan KM, Wang N, Yao X, Huang Y. Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice. Arteriosclerosis, thrombosis, and vascular biology. 2014; 34(1):152-9.
  5. Fazeli PK, Zhang Y, O’keefe JP, Pesaresi T, Lun M, Lawney B, Steinhauser ML. Fasting drives a program of metabolic inflammation in human adipose tissue. Molecular Metabolism. 2020; 242:101082.
  6. Chu AY, Deng X, Fisher VA, Drong A, Zhang Y, Feitosa MF, Liu CT, Weeks O, Choh AC, Duan Q, Dyer TD, Eicher JD, Guo X, Heard-Costa NL, Kacprowski T, Kent JW Jr, Lange LA, Liu X, Lohman K, Lu L, Mahajan A, O'Connell JR, Parihar A, Peralta JM, Smith AV, Zhang Y, Homuth G, Kissebah AH, Kullberg J, Laqua R, Launer LJ, Nauck M, Olivier M, Peyser PA, Terry JG, Wojczynski MK, Yao J, Bielak LF, Blangero J, Borecki IB, Bowden DW, Carr JJ, Czerwinski SA, Ding J, Friedrich N, Gudnason V, Harris TB, Ingelsson E, Johnson AD, Kardia SL, Langefeld CD, Lind L, Liu Y, Mitchell BD, Morris AP, Mosley TH Jr, Rotter JI, Shuldiner AR, Towne B, Völzke H, Wallaschofski H, Wilson JG, Allison M, Lindgren CM, Goessling W, Cupples LA, Steinhauser ML, Fox CS. Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Nature genetics. 2017;49(1):125-130.
  7. Hu W, Zhang Y, Wang L, Lau CW, Xu J, Luo JY, Gou L, Yao X, Chen ZY, Ma RC, Tian XY, Huang Y. Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function. Arteriosclerosis, thrombosis, and vascular biology. 2016;36(3):553-60.

  8. Fazeli PK, Lun M, Kim SM, Bredella MA, Wright S, Zhang Y, Lee H, Catana C, Klibanski A, Patwari P, Steinhauser ML. FGF21 and the late adaptive response to starvation in humans. Journal of clinical investigation. 2015;125(12):4601-11.

  9. Luo JY, Zhang Y, Wang L, Huang Y. Regulators and effectors of bone morphogenetic protein signalling in the cardiovascular system. The Journal of physiology. 2015; 593(14):2995-3011.
  10. Wong CM, Zhang Y, Huang Y. Bone morphogenic protein-4-induced oxidant signaling via protein carbonylation for endothelial dysfunction. Free radical biology & medicine. 2014; 75:178-90.
  11. Tian XY, Wong WT, Leung FP, Zhang Y, Wang YX, Lee HK, Ng CF, Chen ZY, Yao X, Au CL, Lau CW, Vanhoutte PM, Cooke JP, Huang Y. Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2α) impairs endothelial function in renovascular hypertensive rats. Antioxidants & redox signaling. 2012; 16(4):363-73.
  12. Tian XY, Wong WT, Xu A, Lu Y, Zhang Y, Wang L, Cheang WS, Wang Y, Yao X, Huang Y. Uncoupling protein-2 protects endothelial function in diet-induced obese mice. Circulation research. 2012; 110(9):1211-6.

招生信息

接收本科生2-3人/年进行科研培训，招收硕士生2人左右/年。欢迎对心血管和代谢疾病分子机理感兴趣的研究生和本科生加入！