硕士生导师，中山大学百人计划引进人才
研究方向：
- 新型污染物暴露对慢性代谢疾病的毒理影响
- 多组学分析技术的开发与建立
- 食品中新型污染物分析与健康风险评估
科研简介
课题组主要围绕环境污染与健康展开研究工作，关注各种食品中新型污染物的污染特征及其暴露对慢性代谢疾病及神经毒性的影响，利用质谱分析、多组学及分子生物分析手段探究关键毒理机制。已发表SCI论文20余篇，包括Advance Science, Cell Reports, Redox Biology, Analytical Chemistry, Journal of Hazardous Materials, Science of the Total Environment等。主持国家自然科学基金、广东省基础与应用基础等多个项目。担任SCI期刊Environmental geochemistry and health编委、中国分析测试协会生命组学分会委员、广东省毒理学会会员、广东省营养学会个性化精准营养分会会员。
工作经历：
2021.12-至今 中山大学公共卫生学院（深圳），副教授
2019.11-2021.10 香港大学，李嘉诚医学院病理系，博士后
2014.10-2015.8 香港浸会大学，研究助理
教育经历：
2015.9 –2019.11 香港浸会大学，分析化学，博士，导师: 蔡宗苇教授
2011.9 – 2014.6 华侨大学，生物医学学院，硕士
2007.9 – 2011.6 湖北中医药大学，中药学，学士
主要承担课题及人才项目
- 国家自然科学基金青年项目（2023 - 2025），主持，在研
- 广东省自然科学基金面上项目（2024-2026），主持，在研
- 中山大学高校基本科研业务费（2022 - 2022），主持，结题
- 中山大学百人计划引进人才启动项目 （2021 - 2024），主持，结题
- 香港医疗卫生研究基金（HMRF）（2022 - 2025），共同主持（Co-PI），在研
学术兼职
1. 学术期刊副主编：Environmental geochemistry and health
2. 担任多个国际期刊（Redox biology，Environment International, Food and Chemical Toxicology，Biomedicine & Pharmacotherapy, frontier in nutrition等）审稿人
发表论文（*通讯作者）：
Lin, L., Lin, X., Chang, S., Xing, Y., Zhou, T., & Yang, C.* (2025). Age-specific associations between per-and polyfluoroalkyl substances exposure and metabolic syndrome: a cross-sectional study. Lipids in Health and Disease, 24(1), 1-15.
Lin, X., Lin, L., Chang, S., Xing, Y., Zhang, Y., & Yang, C.* (2024). Insights into pollution characteristics and human health risks of plasticizer phthalate esters in shellfish species. Science of The Total Environment, 932, 172984.
Lin, X., Lin, L., Liao, Z., Wu, P., & Yang, C*. (2023). Occurrence and distribution of polycyclic aromatic hydrocarbons (PAHs) in marine organisms from Shenzhen coastal waters and human health risk assessment. Marine Pollution Bulletin, 195, 115498.
Yang C, Jiang Y, Zhao W, et al. Characterization and distribution of polybrominated diphenyl ethers in shellfish in Shenzhen coastal waters and assessment of human health risks. Marine Pollution Bulletin, 2023, 191: 114957.
Yang C, Lee D, Zhang M S, et al. Genome‐Wide CRISPR/Cas9 Library Screening Revealed Dietary Restriction of Glutamine in Combination with Inhibition of Pyruvate Metabolism as Effective Liver Cancer Treatment. Advanced Science, 2022, 9(34): 2202104.
Yang C, Wei J, Cao G, et al. Lipid metabolism dysfunction and toxicity of BDE-47 exposure in white adipose tissue revealed by the integration of lipidomics and metabolomics. Science of The Total Environment, 2022, 806: 150350.
Shen J, Yang C, Zhang MS, Chin WC, Chan FF, Law CT, Wang GC, Cheng CL, Chen M, Wan RT, Wu M, Kuang Z, Sharma R, Lee TK, Ng IO Wong CC#, Wong CM#. Histone chaperone FACT complex coordinates with HIF to mediate expeditious transcription program to adapt to poorly oxygenated cancers. Cell Reports. 2022.
Kang Q, Yang C*. Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications[J]. Redox Biology, 2020: 101799.
Bao M H R#, Yang C#, Tse A P W#, et al. Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer[J]. Cell Reports, 2021, 34(4): 108676.
Yang C, Zhu L, Kang Q, et al. Chronic exposure to tetrabromodiphenyl ether (BDE-47) aggravates hepatic steatosis and liver fibrosis in diet-induced obese mice[J]. Journal of hazardous materials, 2019, 378: 120766.
Yang C, Lee H K, Zhang Y, et al. In situ detection and imaging of PFOS in mouse kidney by matrix-assisted laser desorption/ionization imaging mass spectrometry[J]. Analytical chemistry, 2019, 91(14): 8783-8788.
Yang C, Wong C M, Wei J, et al. The brominated flame retardant BDE 47 upregulates purine metabolism and mitochondrial respiration to promote adipocyte differentiation. Science of The Total Environment, 2018, 644: 1312-1322.
Yang C, Kong A P S, Cai Z, et al. Persistent organic pollutants as risk factors for obesity and diabetes. Current diabetes reports, 2017, 17(12): 1-11.
招生信息：
本实验室欢迎对环境检测、质谱代谢组学、营养毒理、环境毒理与健康等领域感兴趣的且热爱科学研究的研究生和本科生报考与加入！有意者请发送个人简历至 yangchx33@mail.sysu.edu.cn 联系。
